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There are two ongoing ENIGMA-Epilepsy projects: (i) ENIGMA-Epilepsy VOLUMETRICS and (ii) ENIGMA-Epilepsy DTI. Image processing protocols for each project can be found below.

• Step 1: Subcortical volume extraction and visual inspection 
• Step 2: Cortical volume extraction
• Step 3: Steps for Quality Checking of Cortical Volume Outputs
  • (Breakdown of cortical QC code in easy copy/paste format)
  • What is good? What is bad?  Cortical QC – things to look out for! (download PPTX here)

• Step 4: Get population summary statistics of the cortical traits and related histograms

• Step 5: Run case:control regression

• Step 1: Preprocessing (re-directs to the ENIGMA-DTI page)
• Step 2: Skeletonization (start here if you have already preprocessed your data)
• Step 3: Check FA registrations and make sure skeletons are correct 
• Step 4: ROI extraction from FA images
• Step 5: Check the distribution of your ROIs and look for outliers
• Step 6: Analysis (protocol coming soon!)

*For a comprehensive overview of the ENIGMA DTI protocol, please refer to this helpful guide compiled by Dr. Neda Jahanshad: http://enigma.ini.usc.edu/protocols/dti-protocols/