Anyone is welcome to use these protocols for their projects! If you use the protocols on this site for projects outside of ENIGMA, please include a reference to the ENIGMA main page ( so that your readers and reviewers know about it as well. Please also reference the ENIGMA publication if you are using the ENIGMA1 protocols (Stein et al., 2012, Nature Genetics).

ENIGMA Cortical Quality Control Protocol 2.0 (April 2017)

The original ENIGMA Cortical QC protocol was updated in April 2017. While it does not create a departure from the former process and results, it will increase the ease of QC assessment. Thus, the QC 2.0 protocol may be used going forward but does not require any retroactive implementation.