Screen Shot 2015-04-16 at 1.20.46 PM

Current participating members in the ENIGMA-BD working group: Member List

The ENIGMA Bipolar Disorder Working Group was founded in the fall of 2012 and represents an international effort including over 150 clinicians, neuroscientists, bioengineers, and geneticists pooling data and resources to improve bipolar disorder nosology, diagnosis, targeted treatment, and patient outcomes. As part of the wider ENIGMA Consortium we aim to 1) improve efficient and consistent extraction of brain metrics for improved study replication, 2) standardize existing international bipolar disorder data sets to empower large-scale, ecologically valid studies, and 3) perform direct comparisons of brain and clinical measures across psychiatric disorders to better understand the common and distinct markers underlying mental illness on an unprecedented scale.

The Bipolar Disorder Working Group is actively recruiting collaborators. If you have acquired neuroimaging data on individuals with bipolar disorder and are interested in participating, please contact Drs. Ole A. Andreassen and Christopher R. K. Ching.


For more information and details about ongoing ENIGMA-Bipolar working group activities, check out our brochure.

Bipolar Disorder Working Group Memorandum of Understanding (MOU): Bipolar Working Group members are asked to sign a short MOU agreement that has been standardized across the ENIGMA projects and provides basic framework to protect data privacy, facilitate data sharing, encourage academic productivity, ensure appropriate authorship and publication credit, and implements a system to track and archive data, analyses and publications related to the Bipolar Working Group.

Minutes from previous meetings/teleconferences regarding this ENIGMA-Bipolar project can be found here (Password Protected).

ENIGMA Bipolar Disorder Working Group Published Studies:
1. The ENIGMA Bipolar Disorder Working Group in review: Findings and future directions
2. Subcortical structure
3. Hippocampal subfields
4. Cortical structure
5. Machine learning for diagnostic classification
6. White matter microstructure
7. Familial risk across schizophrenia and bipolar disorder
8. Intelligence, educational attainment, and familial risk across schizophrenia and bipolar disorders
9. Shared neurobiology across 6 psychiatric disorders
10. Relationship between neuroimaging and genetic markers across psychiatric disorders
11. Association between body mass index (BMI) and subcotical structures
12. Cortical and subcortical structural correlates of insomnia
13. Associations between body mass index (BMI) and cortical structures
14. Large-scale modeling of longitudinal brain change in bipolar disorder

New ENIGMA-BD WG members can click here for preprocessing resources.

ENIGMA on social media: