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The ENIGMA Bipolar Disorder Working Group (ENIGMA-BD) was founded in the fall of 2012 and represents an international effort including over 200 clinicians, neuroscientists, bioengineers, and geneticists pooling data and resources to improve bipolar disorder nosology, diagnosis, targeted treatment, and patient outcomes. As part of the wider ENIGMA Consortium we aim to 1) improve efficient and consistent extraction of brain metrics for improved study replication, 2) standardize existing international bipolar disorder data sets to empower large-scale, ecologically valid studies, and 3) perform direct comparisons of brain and clinical measures across psychiatric disorders to better understand the common and distinct markers underlying mental illness on an unprecedented scale.

The Bipolar Disorder Working Group is actively recruiting collaborators. If you have acquired neuroimaging data on individuals with bipolar disorder and are interested in participating, please contact ENIGMA-BD chairs Drs. Ole A. Andreassen and Christopher R. K. Ching.

Follow ENIGMA-BD on social media: @enigma_bipolar

Scientific findings from ENIGMA-BD

For more information and details about published, as well as ongoing, ENIGMA-Bipolar working group activities and scientific findings, check out our brochure linked below:


FAQ for patients, families and stakeholders

To explore common questions about bipolar disorder from patients, families, caregivers and advocates, and what we as researchers are doing to improve our knowledge of the disorder, check out our brochure linked below:



Interviews with experts on bipolar disorder

Diagnosis and treatment in bipolar disorder


Member information

Bipolar Disorder Working Group Memorandum of Understanding (MOU): Bipolar Working Group members are asked to sign a short MOU agreement that has been standardized across the ENIGMA projects and provides basic framework to protect data privacy, facilitate data sharing, encourage academic productivity, ensure appropriate authorship and publication credit, and implements a system to track and archive data, analyses and publications related to the Bipolar Working Group.

Minutes from previous meetings/teleconferences regarding this ENIGMA-Bipolar project can be found here (Password Protected).

Current participating members in the ENIGMA-BD working group: Member List

New ENIGMA-BD WG members can click here for preprocessing resources.


ENIGMA Bipolar Disorder Working Group Published Studies:


ENIGMA on social media: