Applications

B. A. Gutman, T. G. M. van Erp, K. Alpert, C. R. K. Ching, D. Isaev, A. Ragothaman, et al., "A meta-analysis of deep brain structural shape and asymmetry abnormalities in 2,833 individuals with schizophrenia compared with 3,929 healthy volunteers via the ENIGMA Consortium," Humam Brain Mapping, vol. 43(1), pp. 352-372, 2022. [link]

T.C. Ho , B. A. Gutman, E. Pozzi E, H.J.Grabe, N. Hosten, K. Wittfeld K, et al., "Subcortical shape alterations in major depressive disorder: Findings from the ENIGMA major depressive disorder working group," Human Brain Mapping, vol. 43(1), pp.341-351, 2022. [link]

C. R. K. Ching, B. A. Gutman, D. Sun, J. E. Villalon Reina, A. Ragothaman, D. Isaev, et al., “Mapping Subcortical Brain Alterations in 22q11.2 Deletion Syndrome: Effects of Deletion Size and Convergence With Idiopathic Neuropsychiatric Illness,” The American Journal of Psychiatry, vol. 177(7), pp. 589-600, 2020. [link]

Y. Chye, S. Mackey, B. A. Gutman, C. R. K. Ching, A. Batalla, S. Blaine, et al., “Subcortical surface morphometry in substance dependence: An ENIGMA addiction working group study,” Addiction biology, vol. 25(6) 2020. [link]

B. S. C. Wade, S. H. Joshi, B. A. Gutman, and P. M. Thompson, "Machine Learning on High Dimensional Shape Data from Subcortical Brain Surfaces: A Comparison of Feature Selection and Classification Methods," Pattern Recognition, vol. 63, pp. 731-739, 2017. [link]

G. V. Roshchupkin*, B. A. Gutman*, M. W. Vernooij, N. Jahanshad, N. G. Martin, A. Hofman, et al., "Heritability of the shape of subcortical brain structures in the general population," Nature Communications, Accepted, 2016. * - equal contribution [link]

B. Li, J. Shi, B. A. Gutman, L. C. Baxter, P. M. Thompson, R. J. Caselli, et al., "Influence of APOE Genotype on Hippocampal Atrophy over Time-An N= 1925 Surface-Based ADNI Study," PloS one, vol. 11, p. e0152901, 2016. [link]

B. S. Wade, S. H. Joshi, S. Njau, A. M. Leaver, M. Vasavada, R. P. Woods , B. A. Gutman, et al., "Effect of Electroconvulsive Therapy on Striatal Morphometry in Major Depressive Disorder," Neuropsychopharmacology, 2016. [link]

D. F. Tate, B. S. C. Wade, C. S. Velez, A. M. Drennon, J. Bolzenius, B. A. Gutman, et al., "Volumetric and Shape Analyses of Subcortical Structures in United States Service Members with Mild Traumatic Brain Injury," Journal of Neurology, vol. 263 (10), pp. 2065-2079, 2016. [link]

B. S. Wade, V. G. Valcour, L. Wendelken-Riegelhaupt, P. Esmaeili-Firidouni, S. H. Joshi, B. A. Gutman, and P. M. Thompson, "Mapping abnormal subcortical brain morphometry in an elderly HIV+ cohort," NeuroImage: Clinical, vol. 9, pp. 564-573, 2015. [link]

J. H. Cole, M. L. Filippetti, M. P. Allin, M. Walshe, K. W. Nam, B. A. Gutman, R. M. Murray, L. Rifkin, P. M. Thompson, and C. Nosarti, "Subregional Hippocampal Morphology and Psychiatric Outcome in Adolescents Who Were Born Very Preterm and at Term," PloS one, vol. 10, p. e0130094, 2015. [link]

F. F. Roussotte, B. A. Gutman, S. K. Madsen, J. B. Colby, K. L. Narr, and P. M. Thompson, "The apolipoprotein E epsilon 4 allele is associated with ventricular expansion rate and surface morphology in dementia and normal aging," Neurobiology of Aging, vol. 35, pp. 1309-1317, 2014. [link]

Y. Wang, Y. Song, P. Rajagopalan, T. An, K. Liu, Y. Y. Chou, B. Gutman, A. W. Toga, and P. M. Thompson, "Surface-based TBM boosts power to detect disease effects on the brain: an N=804 ADNI study," Neuroimage, vol. 56, pp. 1993-2010, Jun 15 2011. [link]

Y. Wang, J. Zhang, B. Gutman, T. F. Chan, J. T. Becker, H. J. Aizenstein, O. L. Lopez, R. J. Tamburo, A. W. Toga, and P. M. Thompson, "Multivariate tensor-based morphometry on surfaces: application to mapping ventricular abnormalities in HIV/AIDS," Neuroimage, vol. 49, pp. 2141-57, Feb 1 2010. [link]

Abstracts

C. Ching, B. Gutman, A. Zavaliangos-Petropulu, D. Sun, R. Jonas, A. Lin, L. Kushan, T. van Amelsvoort, G. Bakker, W. Kates, L. Campbell, K. McCabe, E. Daly, M. Gudbrandsen, C. Murphy, D. Murphy, M. Craig, J. Vorstman, A. Fiksinski, L. Gras, P. Thompson, C. Bearden, for the 22q11.2 ENIGMA Working Group, “22q11.2 Gene Dosage Effects on Subcortical Brain Structure: The ENIGMA 22q11.2 Working Group,” OHBM Annual Meeting, 2016.

B. A. Gutman, C. R. Ching, S. Kelly, K. Alpert, A. Corvin, T. G. Van Erp, J. Turner, P. T. Thompson, and L. Wang, "Meta-Analysis of Subcortical Shape Reveals Differences Between Schizophrenia Patients and Controls.," OHBM Annual Meeting, 2015.

B. A. Gutman, J. Looi, C. R. Ching, and P. T. Thompson, "Subcortical Shape Differences Across Neurodegenrative Diseases," OHBM Annual Meeting, 2015.

C. R. Ching, B. A. Gutman, D. P. Hibar, N. Jahanshad, B. Mwangi, J. C. Soares, and P. M. Thompson, "Subcortical Shape Differences in Bipolar Disorder Subtypes," in Biological Psychiatry, 2015.

Methods

B. A. Gutman, F. Pizzagalli, N. Jahanshad, M. J. Wright2, K. L. McMahon, G. d. Zubicaray, et al., "Approximating Principal Genetic Components of Subcortical Shape," IEEE International Symposium on Biomedical Imaging (ISBI) 2017, accepted, 2017. B. A. Gutman, T. P. Fletcher, G. M. Fleishman, and P. T. Thompson, "Reconstructing Karcher Means of Shapes on a Riemannian Manifold of Metrics and Curvatures," Mathematical Foundations of Computational Analysis, MICCAI 2015, pp. 25-34. [link]

B. A. Gutman, P. T. Fletcher, M. J. Cardoso, G. M. Fleishman, M. Lorenzi, P. M. Thompson, and S. Ourselin, "A Riemannian Framework for Intrinsic Comparison of Closed Genus-Zero Shapes," in Information Processing in Medical Imaging, ed: Springer International Publishing, 2015, pp. 205-218. [link]

B. A. Gutman, N. Jahanshad, C. R. Ching, Y. Wang, P. V. Kochunov, T. E. Nichols, and P. M. Thompson, "Medial demons registration localizes the degree of genetic influence over subcortical shape variability: An N= 1480 meta-analysis," in Biomedical Imaging (ISBI), 2015 IEEE 12th International Symposium on, 2015, pp. 1402-1406. [link]

B. A. Gutman, X. Hua, P. Rajagopalan, Y.-Y. Chou, Y. Wang, I. Yanovsky, A. W. Toga, C. R. Jack Jr, M. W. Weiner, and P. M. Thompson, "Maximizing power to track Alzheimer's disease and MCI progression by LDA-based weighting of longitudinal ventricular surface features," Neuroimage, vol. 70, pp. 386-401, 2013. [link]

B. A. Gutman, S. K. Madsen, A. W. Toga, and P. M. Thompson, "A Family of Fast Spherical Registration Algorithms for Cortical Shapes," in Multimodal Brain Image Analysis, ed: Springer International Publishing, 2013., pp. 246-257. [link]

B. A. Gutman, W. Yalin, P. Rajagopalan, A. W. Toga, and P. M. Thompson, "Shape matching with medial curves and 1-D group-wise registration," in Biomedical Imaging (ISBI), 2012 9th IEEE International Symposium on, 2012, pp. 716-719. [link]

B. Gutman, Y. Wang, J. Morra, A. W. Toga, and P. M. Thompson, "Disease classification with hippocampal shape invariants," Hippocampus, vol. 19, pp. 572-578, Jun 2009. [link]