ENIGMA-Diabetes

Purpose:

Type I and Type 2 Diabetes have been demonstrated to have significant impact on neurocognition, brain structure and function, including development and neurodegeneration. Led by Drs. Shan Luo at the University of Southern California and Tamara Hershey at Washington University in St. Louis, we are initiating the ENIGMA Consortium Diabetes Working Group to integrate Diabetes–related neuroscientific research across the lifespan.

Working Group Goals:

We aim to leverage neuroimaging and diabetes data from cohorts around the world to identify, characterize, and explain how diabetes impacts brain and cognition across the lifespan.
1) Determine how diabetes affects brain development, neurodegeneration, and cognitive functions.
2) Distinguish differences among different types of diabetes in their associations with brain and cognitive function.
3) Study how onset of diabetes, diabetes duration and diabetes management, diabetes medications, and diabetes complications, impact brain and cognition.
4) Identify how lifestyle factors (e.g., diet, exercise, sleep) influence brain and cognitive functions for individuals with diabetes.
5) Determine how sex, race/ethnicity, SES status, neighborhood environment modify the impact of diabetes on brain and cognition.

ENIGMA-Diabetes Working Group Memorandum of Understanding (MOU): ENIGMA Diabetes Group members are asked to sign a short MoU agreement that has been standardized across ENIGMA projects and provides basic framework to protect data privacy, facilitate data sharing, encourage academic productivity, ensure appropriate authorship and publication credit, and implements a system to track and archive data, analyses and publications related to the ENIGMA-Diabetes Working Group.

ENIGMA-DIABETES IS LOOKING FOR NEW MEMBERS!

We are actively searching for international collaborators to join ENIGMA-Diabetes! The only prerequisites for joining as new members are collection of magnetic resonance imaging (MRI) data, information regarding diabetes, and compliance with the ENIGMA Memorandum of Understanding (MOU).

“Can I join if I am unfamiliar with neuroscience of diabetes research?” Yes! Interested cohorts who meet above prerequisites are encouraged to contact us, even if this content area is outside of your current scope of research.

If you are interested in participating, please complete our short data query poll here, and contact the Working Group chairs: Dr Shan Luo (shanluo@usc.edu) and Dr. Tamara Hershey (tammy@wustl.edu).

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