Publicly available datasets to be included in the Regional Vulnerability Index (RVI) project
MPI: Peter Kochunov, Paul Thompson
| Dataset | Clinical population | N controls | N cases | |
|---|---|---|---|---|
| 1 | UK BioBank | Depression, Schizophrenia, Bipolar Disorder, Epilepsy | 25,228 | 4,000 Depression, 21 SCZ, 155 BD, 180 Epilepsy |
| 2 | ADNI | Depression (using GDS; including mild [5-8], moderate [9-11], severe [12+]) | 908 | 79, 216 MCI+, 124 Dementia+ |
| 3 | National Alzheimer's Coordinating Center (NACC) | Depression (using GDS; including mild [5-8], moderate [9-11], severe [12+]) | 2,870 (4,226 total cognitively normal participants available) | pending data proposal submission |
| 4 | OASIS-3 | Depression (using GDS; including mild [5-8], moderate [9-11], severe [12+]) | pending data proposal submission | pending data proposal submission |
| 5 | Consortium for Neuropsychiatric Phenomics (CNP) | Schizophrenia & Depression | 138 | 58 SCZ, 49 BD |
| 6 | Center for Biomedical Research Excellence (COBRE) | Schizophrenia | 99 | 99 |
| 7 | fBIRNPhaseII__0010 | Schizophrenia | 177 | 186 |
| 8 | MIND Clinical Imaging Consortium (MCIC) | Schizophrenia | 164 | 148 |
| 9 | NUSDAST | Schizophrenia | 170 | 171 |
| 10 | BrainGluSchi | Schizophrenia | 89 | 86 |
| 11 | NMorphCH | Schizophrenia | 44 | 46 |
| 12 | REWARD | Schizophrenia | 39 | 59 |
| 13 | SchizConnect - from BrainGluSchi, COBRE, fBIRN, MCIC, NMorphCH, NUSDAST, and REWARD | Bipolar Disorder | calculated per dataset in rows above | 10 |
| 14 | MPRC (to be shared on NDAR) | Schizophrenia | 400 | 324 |
| 15 | Bipolar & Schizophrenia Consortium for Parsing Intermediate Phenotypes (B-SNIP 1) | Bipolar Disorder, Schizophrenia | 1,703 total | |
| 16 | Amish Connectome Project on Mental Illness (ACP) | Depression, Schizophrenia, Bipolar Disorder | 343 of 450 are uploaded | |
| 17 | Towards Multisystem-Brain Successful Aging in Schizophrenia Spectrum (BCC) | Schizophrenia | 92 of 210 are uploaded (100pt/110ct) | |
| 18 | Kynurenic Acid and Cognitive Abnormalities in Schizophrenia (NCB) | Schizophrenia | 13 of 160 are uploaded | |
| 19 | 7T MRI to reveal structural, connectomic and metabolic imaging markers for the neurobiology of depression | Depression | 49 are uploaded (enrolling) | |
| 20 | Development of Attention Bias Modification for Depression | Depression | 146 total | |
| 21 | Neurobehavioral Mechanisms of Emotion Regulation in Depression across the Adult Lifespan | Depression | 53 of 200 are uploaded | |
| 22 | Cerebellar metabolism, neural circuits, and symptoms in bipolar disorder | Bipolar Disorder | 97 uploaded (enrolling) | |
| 23 | Children of Bipolar Parents: A High Risk Follow Up Study (also known as Bipolar Offspring Study - BIOS) | Bipolar Disorder | 38 of 140 are uploaded | |
| 24 | Course and Outcome of Bipolar Disorder in Youth (COBY) | Bipolar Disorder | 50 | 102 of 20 are uploaded |
| 25 | The contribution of aberrant anticipatory processing to spectrum depression and mania, and cognitive and emotional dysfunction in major depressive and bipolar disorders | Depression, Bipolar Disorder | N/A | 97 of 150 are uploaded |
| 26 | Advancing innovative brain imaging to detect altered glutamate modulation and network dynamics in schizophrenia | Schizophrenia | 91 of 195 are uploaded | |
