Anyone is welcome to use these protocols for their projects! If you use the protocols on this site for projects outside of ENIGMA, please include a reference to the ENIGMA main page ( so that your readers and reviewers know about it as well.

ComBat for ENIGMA

ComBat is a function that allows for removal of known batch effects. This modified version of the function for the ENIGMA Consortium also allows to separate functions for fitting and applying the harmonization, and allows missings and constant rows and minor changes in the arguments of the functions to facilitate their use.
Please cite “Increased power by harmonizing structural MRI site differences with the ComBat batch adjustment method in ENIGMA” (Radua et al., NeuroImage 2020; in press)


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